Courses

Search for courses listed in this bulletin. To find a semester course schedule (including instructors, meeting times and locations), go to mynmu.nmu.edu.

CLS 382 Histotechnique III 3 cr.
  • Offered: Fall Winter
  • Prerequisites: Completion of the required courses in the histotechnician or histotechnologist curriculum and acceptance by a clinical agency with an accredited histology training program.
Clinical experience includes grossing, embedding and microscopy. This course is part of a supervised, full-time, 6-month to 12-month clinical practicum in an accredited histology program. The practicum prepares students to assist in tissue-related procedures to establish and confirm a patient’s diagnosis. The preparation and staining of tissue involves a variety of techniques. The practicum is represented by CLS 250H, CLS 380, CLS 381, CLS 382, CLS 383 and CLS 384.
CLS 383 Histochemistry and Pathology 8 cr.
  • Offered: Fall Winter
  • Prerequisites: Completion of the required courses in the histotechnician or histotechnologist curriculum and acceptance by a clinical agency with an accredited histology training program.

Clinical experience includes special staining, electron microscopy, and DNA. This course is part of a supervised, full-time, 6-month to 12-month clinical practicum in an accredited histology program. The practicum prepares students to assist in tissue-related procedures to establish and confirm a patient’s diagnosis. The preparation and staining of tissue involves a variety of techniques. The practicum is represented by CLS 250H, CLS 380, CLS 381, CLS 382, CLS 383 and CLS 384.

CLS 384 Advanced Histology 5 cr.
  • Offered: Fall Winter
  • Prerequisites: Completion of the required courses in the histotechnician or histotechnologist curriculum and acceptance by a clinical agency with an accredited histology training program.
Clinical experience includes special projects, management, and legal procedures. This course is part of a supervised, full-time, 6-month to 12-month clinical practicum in an accredited histology program. The practicum prepares students to assist in tissue-related procedures to establish and confirm a patient’s diagnosis. The preparation and staining of tissue involves a variety of techniques. The practicum is represented by CLS 250H, CLS 380, CLS 381, CLS 382, CLS 383 and CLS 384.
CLS 391 Laboratory Experience 1-3 cr.
  • Offered: Fall Winter Summer
  • Prerequisites: Permission of supervising faculty and program director.

A course subtitle on the student’s transcript will describe the content for this course, e.g. CLS 391 Laboratory Experience in Hematology Student Laboratory. The course is designed to offer additional experience in the student laboratory which may involve instrument set-up, shut down, troubleshooting, trialing procedures before implementation, laboratory maintenance, reagent preparation, and assisting the instructor.

Notes:

May be repeated if topic differs up to six credit hours.

CLS 401 Hematopathology 3 cr.
  • Offered: Winter
  • Prerequisites: CLS 201 (CLS 251 recommended, or instructor's permission).

Survey of hematopoiesis, blood cell derivation, iron metabolism, erythropoiesis, physiological classification and laboratory investigation of anemias, leukocyte and platelet physiology and function, and disorders of phagocytosis. Key laboratory tests are identified with each area of assessment. Learning activities include computer-assisted instruction, laboratory problems and correlation of clinical data.

CLS 402 Advanced Clinical Chemistry 2 cr.
  • Offered: Fall
  • Prerequisites: CLS 202 (CLS 252 and DATA 109 recommended).

A lecture-laboratory course involving a problem-solving orientation to laboratory practice. Learning activities include a laboratory method comparison, laboratory problems of technical and diagnostic focus, written assignments pertaining to hormones and therapeutic drugs, and computer-assisted instruction.

CLS 403 Advanced Immunohematology 2 cr.
  • Offered: Winter
  • Prerequisites: CLS 203 (CLS 253 recommended, or instructor's permission).

Advanced studies in antibody-antigen interaction in relation to blood component therapy. Learning activities include laboratory problems and CAI focusing on complex blood-banking problems; a written assignment for selection of methods for clinical analysis and special techniques in laboratory practice.

CLS 404 Advanced Clinical Microbiology I 2 cr.
  • Offered: Fall
  • Prerequisites: CLS 204 and CLS 214 (CLS 254 recommended, or instructor's permission).

A study of selected topics in bacteriology, mycology, parasitology and virology utilizing computer-assisted instruction, written assignments and lab problems. Identification techniques and protocol will be evaluated for both common and infrequently isolated pathogens.

CLS 410 Introduction to Clinical Management 1 cr.
  • Offered: Fall Winter
  • Prerequisites: MA 109, junior standing, and a declared major in the Clinical Sciences Department.

Designed to provide introduction to management issues and practices in the clinical environment such as human resources, leadership, finances, regulatory oversight, compliance issues and productivity/benchmarking. The course will be offered on-line.

CLS 412 Clinical Biochemistry 3 cr.
  • Offered: Fall
  • Prerequisites: CLS 402 or CH 220.

This course focuses on clinically important organic and biochemical molecules such as carbohydrates, proteins, heme-derivatives, lipids, lipo-proteins, hormones, tumor markers, therapeutic drugs, toxins, and drugs of abuse. Focus is given to structure, nomenclature, biochemical mechanism, and the use of these molecules as biomarkers to assess health and disease. Advanced mass spectrometry based technologies used in diagnostic laboratories methods is included.

Notes:

This course can only be repeated once.

CLS 413 Advanced Clinical Immunology 3 cr.
  • Offered: Winter
  • Prerequisites: CLS 402.

This course covers principles of clinical immunology to include: physiology of immunity, humoral and cell mediated immunity, innate and adaptive immunity, and normal versus pathophysiological immune responses.  Advanced immunological methods used to diagnose and evaluate allergy, autoimmunity, infectious disease, and transplant compatibility such as DFA, EIA, ELISA, Western Blot, and Chemiluminesence are covered along with focus on the use of diagnostic algorithms.

Notes:

This course can only be repeated once with instructor permission.

CLS 414 Advanced Clinical Microbiology II 3 cr.
  • Offered: Fall
  • Prerequisites: CLS 404.

This course covers advanced concepts in clinical disease caused by difficult to culture and novel bacteria, fungi, viruses, macro and micro parasites, and prions. Emphasis is placed on emerging detection and identification technologies to include MALDI-TOF MS, PCR-ESI-MS, 16s Sequencing, and microarrays. Advanced concepts involve the combination of pathogen virulence, resulting clinical signs and symptoms, and the use of diagnostic algorithms to guide testing decisions.

Notes:

This course can only be repeated once with instructor permission.

CLS 416 Diagnostic Genetics, Genomics, and Cytogenetics 4 cr.  (2-0-5)
  • Offered: Winter
  • Prerequisites: BI 312, CLS 436 or CH 450, junior standing, or instructor permission.

The course covers the theory, technique, and applications of diagnostic molecular technologies. Topics include nucleic acid extraction, polymerase chain reaction, isothermal amplification techniques, and genomic technologies to include microarray, Sanger sequencing, and Next Generation Sequencing and the role of Bioinformatics in the diagnosis of inherited, acquired, and infectious disease.  The course also includes cytogenetic techniques used to detect genetic disease. The course is designed for all CLS majors and for Biology or Biochemistry majors interested in medical diagnostic applications.

CLS 420 Clinical Educational Practices 1 cr.
  • Offered: Fall Winter
  • Prerequisites: Junior standing or instructor's permission.

Introduction of the laboratory professional to basic education methodology. The principles of learning, the use of goals and objectives and the analysis of a teaching module will be addressed first. Students will be required to teach two laboratory sessions and present one in-service to the Clinical Laboratory Sciences Department.

CLS 426 Clinical Molecular Diagnostics 3 cr.
  • Offered: Winter
  • Prerequisites: BI 218 or CLS 402 or instructor permission.

This course covers the theory and application of nucleic acid based technologies to detect and characterize inherited disorders, acquired genetic diseases, and infectious disease. The principles of PCR based methods, SDA, HDA, LCR, TMA, NASBA, LAMP, sequencing methods and microarray analysis are covered. The use of these technologies for the detection and characterization of human pathologies is emphasized with a focus on the selection of each for specific diseases in clinical settings.

Notes:

This course can only be repeated once with instructor permission.

CLS 436 Medical Genetics 4 cr.
  • Offered: Fall
  • Prerequisites: BI 218 or BI 312 or CLS 426.

 

This course is designed to teach basic principles of medical genetics and the application of these principles to our understanding of human genetic diseases and disabilities. In addition, this course will help students gain a better understanding of the role of genetics in ongoing developments in patient care. Topics span the following areas: infectious diseases, hematology/oncology, and molecular genetics.

 

CLS 440 Advanced Clinical Bacteriology 8 cr.
  • Offered: Fall Winter
  • Prerequisites: A grade of "C" or better in all CLS courses, a minimum of 2.60 NMU cumulative GPA and 2.50 GPA in the major, CLT certification and CLS faculty recommendation. Junior standing or instructor’s permission. Students must also enroll in CLS 250M during the summer months.

This course is part of an intense, five-month, full-time practicum in an approved clinical laboratory under the supervision of a clinical laboratory scientist or microbiologist. Includes practical experience with emphasis on proficiency, special or unique procedures, problem solving, method evaluation and supervisory functions. The practicum is represented by CLS 250M, CLS 440, CLS 441, CLS 442 and CLS 443.

CLS 441 Advanced Clinical Mycology 2 cr.
  • Offered: Fall Winter
  • Prerequisites: A grade of "C" or better in all CLS courses, a minimum of 2.60 NMU cumulative GPA and 2.50 GPA in the major, CLT certification and CLS faculty recommendation. Junior standing or instructor’s permission. Students must also enroll in CLS 250M during the summer months.

This course is part of an intense, five-month, full-time practicum in an approved clinical laboratory under the supervision of a clinical laboratory scientist or microbiologist. Includes practical experience with emphasis on proficiency, special or unique procedures, problem solving, method evaluation and supervisory functions. The practicum is represented by CLS 250M, CLS 440, CLS 441, CLS 442 and CLS 443.

CLS 442 Advanced Clinical Parasitology 2 cr.
  • Offered: Fall Winter
  • Prerequisites: A grade of "C" or better in all CLS courses, a minimum of 2.60 NMU cumulative GPA and 2.50 GPA in the major, CLT certification and CLS faculty recommendation. Junior standing or instructor’s permission. Students must also enroll in CLS 250M during the summer months.

This course is part of an intense, five-month, full-time practicum in an approved clinical laboratory under the supervision of a clinical laboratory scientist or microbiologist. Includes practical experience with emphasis on proficiency, special or unique procedures, problem solving, method evaluation and supervisory functions. The practicum is represented by CLS 250M, CLS 440, CLS 441, CLS 442 and CLS 443.

CLS 443 Advanced Clinical Mycobacteriology/Virology 2 cr.
  • Offered: Fall Winter
  • Prerequisites: A grade of "C" or better in all CLS courses, a minimum of 2.60 NMU cumulative GPA and 2.50 GPA in the major, CLT certification and CLS faculty recommendation. Junior standing or instructor’s permission. Students must also enroll in CLS 250M during the summer months.

This course is part of an intense, five-month, full-time practicum in an approved clinical laboratory under the supervision of a clinical laboratory scientist or microbiologist. Includes practical experience with emphasis on proficiency, special or unique procedures, problem solving, method evaluation and supervisory functions. The practicum is represented by CLS 250M, CLS 440, CLS 441, CLS 442 and CLS 443.

CLS 451 Advanced Clinical Hematology Practicum 3 cr.
  • Offered: Fall Winter
  • Prerequisites: A grade of “C” or better in all CLS courses; a minimum 2.60 NMU cumulative GPA, a minimum 2.50 GPA in the major, CLT certification and recommendations. Junior standing or instructor’s permission.

Includes hematology and coagulation.

Notes:

This course is part of an intense, five-month, full-time practicum in an affiliated clinical laboratory under supervision of clinical laboratory scientists. Includes practical experience and further acquisition of theoretical principles in all areas of the clinical laboratory with emphasis on special testing, problem solving and a variety of supervisory functions. The practicum is represented by CLS 250S, CLS 451, CLS 452, CLS 453, and CLS 454.

CLS 452 Advanced Clinical Chemistry Practicum 3 cr.
  • Offered: Fall Winter
  • Prerequisites: A grade of “C” or better in all CLS courses; a minimum 2.60 NMU cumulative GPA, a minimum 2.50 GPA in the major, CLT certification and recommendations. Junior standing or instructor’s permission.

Includes chemistry and special testing.

Notes:

This course is part of an intense, five-month, full-time practicum in an affiliated clinical laboratory under supervision of clinical laboratory scientists. Includes practical experience and further acquisition of theoretical principles in all areas of the clinical laboratory with emphasis on special testing, problem solving and a variety of supervisory functions. The practicum is represented by CLS 250S, CLS 451, CLS 452, CLS 453, and CLS 454.

CLS 453 Advanced Clinical Immunohematology Practicum 4 cr.
  • Offered: Fall Winter
  • Prerequisites: A grade of “C” or better in all CLS courses; a minimum 2.60 NMU cumulative GPA, a minimum 2.50 GPA in the major, CLT certification and recommendations. Junior standing or instructor’s permission.

Includes blood banking and serology areas.

Notes:

This course is part of an intense, five-month, full-time practicum in an affiliated clinical laboratory under supervision of clinical laboratory scientists. Includes practical experience and further acquisition of theoretical principles in all areas of the clinical laboratory with emphasis on special testing, problem solving and a variety of supervisory functions. The practicum is represented by CLS 250S, CLS 451, CLS 452, CLS 453, and CLS 454.

CLS 454 Advanced Clinical Microbiology Practicum 4 cr.
  • Offered: Fall Winter
  • Prerequisites: A grade of “C” or better in all CLS courses; a minimum 2.60 NMU cumulative GPA, a minimum 2.50 GPA in the major, CLT certification and recommendations. Junior standing or instructor’s permission.

Includes bacteriology, mycology, parasitology and virology.

Notes:

This course is part of an intense, five-month, full-time practicum in an affiliated clinical laboratory under supervision of clinical laboratory scientists. Includes practical experience and further acquisition of theoretical principles in all areas of the clinical laboratory with emphasis on special testing, problem solving and a variety of supervisory functions. The practicum is represented by CLS 250S, CLS 451, CLS 452, CLS 453, and CLS 454.

CLS 460 Specimen Processing and Culture 4 cr.
  • Offered: Fall Winter
  • Prerequisites: Students must achieve a B- or better in all 100-200 level CLS courses and BI218 and a B or better in all 300-400 level CLS courses and BI 312, BI406, BI 418 and CH454. Completion of the pre-clinical courses in the diagnostics genetics curriculum and acceptance by an affiliated clinical agency.

This course is part of an intense, six-month, full-time practicum in an affiliated full-service laboratory under supervision of appropriately credentialed cytogenetics professionals. Some hospital affiliates may require a nine-month practicum. Includes practical experience and theoretical principles in areas described by CLS 250G, CLS 460, CLS 461, CLS 462 and CLS 463.